The United Nations Convention on the Rights of the Child (UNCRC) is presented and understood as the primary reference point regarding questions of children’s rights. However, the UNCRC is not a neutral instrument deployed to meet the rights of children: it embodies a specific perception of the child, childhood and citizenship. The interpretation of the UNCRC from the point of view of children’s legal status emphasises the autonomy of children; the focus is on the rights that children possess. Conversely, the (...) social-political interpretation of the UNCRC addresses the question of how the rights of children can be realised. It is suggested that distinguishing between these interpretations is essential with regard to questions of pedagogy and education. (shrink)

Denne artikkelen tar utgangspunkt i et skille mellom samfunnsstrukturer som avgrenser legers skjønnsmessige utfoldelse på den ene siden, og profesjonens tilrettelegging for kultiveringen av erkjennelsesmessige ferdigheter på den annen. Ved å videreføre H. Grimen og A. Molanders anvendelse av S.E. Toulmins modell for praktisk resonnering i en klinisk kontekst redegjør jeg for legeskjønnets multidimensjonale, epistemiske struktur. Gjennomgangen viser hvordan skjønnsanvendelse i legerollen kan analyseres i henhold til en fagteknisk, en distributiv og en relasjonell dimensjon. Mot denne bakgrunnen diskuterer jeg så (...) spenninger som oppstår i skjæringspunktet mellom strukturering og kultivering av skjønnets ulike dimensjoner. Diskusjonen tydeliggjør at den medisinske profesjonen ikke kan betraktes som en selvtilstrekkelig premissleverandør når det gjelder å sikre adekvat kultivering av medlemmenes skjønnsutøvelse i en klinisk kontekst. Ved å synliggjøre og vektlegge de relevante profesjonseksterne bidragene i profesjonens pågående selvregulering kan befolkningens berettigete tillit til profesjonen styrkes ytterligere.Nøkkelord: strukturelt skjønn, epistemisk skjønn, profesjon, selvregulering, tillitEnglish summary: In Between Structures of Society and Profession: On Delimitation, Cultivation and Premises for Adequately Exercising Judgment in the Role as PhysicianThe point of departure of this article is a distinction between societal structures that delimit the discretion of the physician on the one hand and the profession's arrangements for the cultivation of the physician's judgment on the other. By developing H. Grimen and A. Molander's application of S.E. Toulmin's model for practical reasoning in a clinical context, the multi-dimensional epistemic structure of the physician's judgment in terms of technical, distributive, and relational judgment is accounted for. Against this backdrop, tensions emerging in the intersection between delimitation and cultivation of professional judgment in its various dimensions are discussed. The discussion clarifies that the medical profession is not a self-sufficient provider when it comes to ensuring an adequate cultivation of its members' judgment in a clinical context. It is argued that by emphasising and implementing the relevant external contributions to the profession's ongoing self-regulation, the public's justified trust in the medical profession can be strengthened. (shrink)

I Norge er ikke surrogati tillatt, og myndighetene fraråder norske statsborgere å benytte seg av surrogati i utlandet. I denne artikkelen fokuserer vi på kommersiell gestational surrogati og stiller spørsmålet: Bør man tillate at norske statsborgere benytter seg av surrogati i India? De etiske problemstillingene rundt surrogati er mange og sammensatte og blir spesielt utfordrende når tjenesten tilbys i et land med store kulturelle og økonomiske forskjeller både internt og i forhold til Norge. Vi baserer analysen og drøftingen av dette (...) etisk utfordrende spørsmålet på Beauchamps og Childress sin veletablerte metodiske tilnærming innen biomedisinsk etikk. Vi anvender de fire allmennmoralske prinsipper: respekt for autonomi, velgjørenhet, ikke-skade og rettferdighet på sakskomplekset for å synliggjøre spenningene involvert i dette etiske dilemmaet. Med full bevissthet om at det ikke finnes noen lettvinte og omkostningsfrie løsninger på dilemmaer generelt og dette spesielt, konkluderer vi med at interessene til de berørte parter, og spesielt surrogatmødrenes, kan bli bedre ivaretatt om surrogati tillates under omfattende reguleringer. Dersom man velger å gjøre praksisen illegal, vil man også miste mulighetene til å påvirke prosessen og sikre rettighetene til de involverte partene.Nøkkelord: surrogati, Norge–India, utnyttelse, autonomi, regulering av prosessenEnglish summary: Should Norwegian citizens be permitted to use surrogacy in India?Surrogacy is not permitted in Norway, and the government strongly advises against Norwegian citizens travelling abroad to have children through the use of the surrogacy industry. In this article, we focus on commercial gestational surrogacy and debate the question: Should Norwegian citizens be permitted to use surrogacy in India? The ethical concerns regarding surrogacy are complex and are especially challenging when the service is offered in a country with big cultural and economic differences both internal and in comparison to Norway. We base our analysis of this ethical, challenging question on Beauchamp’s and Childress’s well-established approach within biomedical ethics. We apply the four principles of respect for autonomy, beneficence, nonmaleficence and justice to shed light on the conflicts of interests in this ethical dilemma. With full awareness that there are no simple and correct solutions to dilemmas in general and on this issue, especially, our conclusion is that the interests of the involved parties, and especially those of the surrogate mothers, might be better attended to if surrogacy is allowed with extensive regulations. If this practice is made illegal, the opportunity to influence the process and secure the rights of the involved parties is lost. (shrink)

The COVID-19 pandemic has forced developmental researchers to rethink their traditional research practices. The growing need to study infant development at a distance has shifted our research paradigm to online and digital monitoring of infants and families, using electronic devices, such as smartphones. In this practical guide, we introduce the Experience Sampling Method – a research method to collect data, in the moment, on multiple occasions over time – for examining infant development at a distance. ESM is highly suited for (...) assessing dynamic processes of infant development and family dynamics, such as parent-infant interactions and parenting practices. It can also be used to track highly fluctuating family dynamics and routines. The aim of the current paper was to provide an overview by explaining what ESM is and for what types of research ESM is best suited. Next, we provide a brief step-by-step guide on how to start and run an ESM study, including preregistration, development of a questionnaire, using wearables and other hardware, planning and design considerations, and examples of possible analysis techniques. Finally, we discuss common pitfalls of ESM research and how to avoid them. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Progressive supranuclear palsy is a movement disorder with prominent tau neuropathology. Brain diseases with abnormal tau deposits are called tauopathies, the most common of which is Alzheimer's disease. Environmental causes of tauopathies include repetitive head trauma associated with some sports. To identify common genetic variation contributing to risk for tauopathies, we carried out a genome-wide association study of 1,114 individuals with PSP and 3,247 controls followed by a second stage in which we genotyped 1,051 cases and 3,560 controls for the (...) stage 1 SNPs that yielded P ≤ 10-3. We found significant previously unidentified signals associated with PSP risk at STX6, EIF2AK3 and MOBP. We confirmed two independent variants in MAPT affecting risk for PSP, one of which influences MAPT brain expression. The genes implicated encode proteins for vesicle-membrane fusion at the Golgi-endosomal interface, for the endoplasmic reticulum unfolded protein response and for a myelin structural component. © 2011 Nature America, Inc. All rights reserved. (shrink)

© 2016 Regents of the University of California.The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,062 new measurements from 721 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark photons, etc. All the particle properties and search limits are listed in Summary Tables. We also give numerous (...) tables, figures, formulae, and reviews of topics such as Higgs Boson Physics, Supersymmetry, Grand Unified Theories, Neutrino Mixing, Dark Energy, Dark Matter, Cosmology, Particle Detectors, Colliders, Probability and Statistics. Among the 117 reviews are many that are new or heavily revised, including those on Pentaquarks and Inflation. The complete Review is published online in a journal and on the website of the Particle Data Group. The printed PDG Book contains the Summary Tables and all review articles but no longer includes the detailed tables from the Particle Listings. A Booklet with the Summary Tables and abbreviated versions of some of the review articles is also available. (shrink)

The intention here is that of giving a formal underpinning to the idea of 'meaning-is-use' which, even if based on proofs, it is rather different from proof-theoretic semantics as in the Dummett-Prawitz tradition. Instead, it is based on the idea that the meaning of logical constants are given by the explanation of immediate consequences, which in formalistic terms means the effect of elimination rules on the result of introduction rules, i. e. the so-called reduction rules. For that we suggest an (...) extension to the Curry-Howard interpretation which draws on the idea of labelled deduction, and brings back Frege's device of variable-abstraction to operate on the labels (i. e., proof-terms) alongside formulas of predicate logic. (shrink)

Although classical evolutionary theory, i.e., population genetics and the Modern Synthesis, was already implicitly ‘gene-centred’, the organism was, in practice, still generally regarded as the individual unit of which a population is composed. The gene-centred approach to evolution only reached a logical conclusion with the advent of the gene-selectionist or gene’s eye view in the 1960s and 1970s. Whereas classical evolutionary theory can only work with (genotypically represented) fitness differences between individual organisms, gene-selectionism is capable of working with fitness differences (...) among genes within the same organism and genome. Here, we explore the explanatory potential of ‘intra-organismic’ and ‘intra-genomic’ gene-selectionism, i.e., of a behavioural-ecological ‘gene’s eye view’ on genetic, genomic and organismal evolution. First, we give a general outline of the framework and how it complements the—to some extent—still ‘organism-centred’ approach of classical evolutionary theory. Secondly, we give a more in-depth assessment of its explanatory potential for biological evolution, i.e., for Darwin’s ‘common descent with modification’ or, more specifically, for ‘historical continuity or homology with modular evolutionary change’ as it has been studied by evolutionary developmental biology (evo-devo) during the last few decades. In contrast with classical evolutionary theory, evo-devo focuses on ‘within-organism’ developmental processes. Given the capacity of gene-selectionism to adopt an intra-organismal gene’s eye view, we outline the relevance of the latter model for evo-devo. Overall, we aim for the conceptual integration between the gene’s eye view on the one hand, and more organism-centred evolutionary models (both classical evolutionary theory and evo-devo) on the other. (shrink)

Although classical evolutionary theory, i.e., population genetics and the Modern Synthesis, was already implicitly ‘gene-centred’, the organism was, in practice, still generally regarded as the individual unit of which a population is composed. The gene-centred approach to evolution only reached a logical conclusion with the advent of the gene-selectionist or gene’s eye view in the 1960s and 1970s. Whereas classical evolutionary theory can only work with fitness differences between individual organisms, gene-selectionism is capable of working with fitness differences among genes (...) within the same organism and genome. Here, we explore the explanatory potential of ‘intra-organismic’ and ‘intra-genomic’ gene-selectionism, i.e., of a behavioural-ecological ‘gene’s eye view’ on genetic, genomic and organismal evolution. First, we give a general outline of the framework and how it complements the—to some extent—still ‘organism-centred’ approach of classical evolutionary theory. Secondly, we give a more in-depth assessment of its explanatory potential for biological evolution, i.e., for Darwin’s ‘common descent with modification’ or, more specifically, for ‘historical continuity or homology with modular evolutionary change’ as it has been studied by evolutionary developmental biology during the last few decades. In contrast with classical evolutionary theory, evo-devo focuses on ‘within-organism’ developmental processes. Given the capacity of gene-selectionism to adopt an intra-organismal gene’s eye view, we outline the relevance of the latter model for evo-devo. Overall, we aim for the conceptual integration between the gene’s eye view on the one hand, and more organism-centred evolutionary models on the other. (shrink)

Open-content communities that focus on co-creation without requirements for entry have to face the issue of institutional trust in contributors. This research investigates the various ways in which these communities manage this issue. It is shown that communities of open-source software—continue to—rely mainly on hierarchy (reserving write-access for higher echelons), which substitutes (the need for) trust. Encyclopedic communities, though, largely avoid this solution. In the particular case of Wikipedia, which is confronted with persistent vandalism, another arrangement has been pioneered instead. (...) Trust (i.e. full write-access) is ‘backgrounded’ by means of a permanent mobilization of Wikipedians to monitor incoming edits. Computational approaches have been developed for the purpose, yielding both sophisticated monitoring tools that are used by human patrollers, and bots that operate autonomously. Measures of reputation are also under investigation within Wikipedia; their incorporation in monitoring efforts, as an indicator of the trustworthiness of editors, is envisaged. These collective monitoring efforts are interpreted as focusing on avoiding possible damage being inflicted on Wikipedian spaces, thereby being allowed to keep the discretionary powers of editing intact for all users. Further, the essential differences between backgrounding and substituting trust are elaborated. Finally it is argued that the Wikipedian monitoring of new edits, especially by its heavy reliance on computational tools, raises a number of moral questions that need to be answered urgently. (shrink)

Modelos neurocognitivos têm sido propostos para investigar a consciência. O objetivo é responder à pergunta sobre como o cérebro é capaz de produzir estados conscientes qualitativos. Os modelos são representações teóricas baseadas em algumas pesquisas empíricas. Contudo, a questão central, aparentemente trivial para alguns autores, refere-se à representatividade e confiabilidade dos modelos, i.e., saber se são capazes de explicar como a consciência emerge de processos neurais. Esses modelos são considerados como guia no estudo científico da consciência: os modelos cognitivos de (...) Dennett e Baars, os modelos neurobiológicos de Edelman, Dehaene et al., de Damásio, e o modelo neurodinâmico proposto por Freeman. O presente texto visa a analisar a coerência e a plausibilidade dos modelos, i.e., se realmente explicam a “consciência” e suas propriedades em termos neurais ou se explicam apenas mecanismos neurobiológicos subjacentes no cérebro. O objetivo é avaliar escopo e limites dos modelos além da aplicabilidade na resolução do problema da consciência. Neurocognitive models are proposed in order to study the problem of consciousness. The models are attempts to answer the question of how the brain can generate conscious and qualitative states. Models are theoretical representations based on empirical data. Nonetheless, the central question concerns the reliability and the representativeness of the models, i.e., whether they in fact represent what they are supposed to explain, viz., how consciousness can emerge from neuronal processes. Such models are taken to be a guide for the scientific study of consciousness. Presently, there are six models: the multiple draft, the global workspace, the dynamic core, the global neuronal workspace, the somatic markers hypothesis, and the neurodynamic model. This text is a survey and a philosophical analysis of the models of consciousness, and it considers their plausibility and coherence. I will concentrate on two points: whether the neuroscientific models are able to explain ‘consciousness’ and its properties in neural terms, or whether the models only explain the neural correlates of conscious states, and the scope, limitations and applicability of the models in the attempt to solve the problem of consciousness. (shrink)

The intention here is that of giving a formal underpinning to the idea of ‘meaning-is-use’ which, even if based on proofs, it is rather different from proof-theoretic semantics as in the Dummett–Prawitz tradition. Instead, it is based on the idea that the meaning of logical constants are given by the explanation of immediate consequences, which in formalistic terms means the effect of elimination rules on the result of introduction rules, i.e. the so-called reduction rules. For that we suggest an extension (...) to the Curry– Howard interpretation which draws on the idea of labelled deduction, and brings back Frege’s device of variable-abstraction to operate on the labels (i.e., proof-terms) alongside formulas of predicate logic. (shrink)

As a contribution to the commemorations of Spinoza's death, this article describes in a few pages the significance of Spinoza in the evolution of Western political thought. Especially in his Political Treatise, Spinoza attempted to elaborate a «scientific» theory of political life, i.e. a closing deductive theory based upon a «true knowledge of the causes and natural bases» of human actions and passions. In his view it can be proved with a rational necessity that democracy - defined as Spinoza defines (...) it - is the best political regime. He strongly emphasizes that democracy and, consequently, a well organized and efficiently functioning life in common, is impossible without real freedom of opinion and speech and a political «neutralization» of religion. (shrink)

No satisfactory treatment of the whole subject of jurisdiction in the Athenian Empire of the fifth century B.C. yet exists, and in this paper I make no attempt to provide a complete account. My purpose is twofold: to deal in some detail with certain specific problems, and to demonstrate that the most fruitful method of approach to the whole subject—perhaps, indeed, the only one which can reduce it to order–is to divide it up under three particular headings and to treat (...) each of these separately. Only Part I will be included in the present issue of this journal; Parts II and III, with a brief Conclusion, will appear in a later issue. (shrink)

The text of Kant’s first dissertation is a translation from Latin from an academic publication of a collection of Kant’s works: Kant, I. Meditationum quarundam de igne succincta delineatio... In: Königlich Preußischen Akademie der Wissenschaften, ed., 1910. Kants Gesammelte Schriften. 1. Abhandling: Werke. Band I: Vorkritische Schriften I, 1747-1756. Berlin: Georg Reimer, 1910, pp. 369-384. The publication is available at https://korpora.zim.uni-duisburg- essen.de/kant/aa01/ [Accessed 10 March 2019]. Pagination and illustrations are from the same publication, the page numbers are in square brackets (...) at the beginning of the page. Page footnotes, if indicated, draw on the commentaries of Lewis White Beck, the translator of the dissertation into English from the following edition: Kant, I., 2012. Natur­al Science, edited by E. Watkins, translated by L. W. Beck, J. B. Edwards, O. Reinhardt, M. Schönfeld and E. Watkins. Cambridge: Cambridge University Press, pp. 713-714. It was important for the translator to follow the course of Kant’s thought and as far as possible preserve his style, including recurring words. Natural science terminology keeps as close as possible to the dissertation text, so instead of the term “gas”, which Kant does not use, the translator resorts to a loan-translation “elastic liquid,” harking back to the Russian term упругая жидкость which was proposed by Mikhail V. Lomonosov but did not catch on. For the same reason the translator uses the loan translation “moment” instead of the more common “motive force”. “Gradus”, however, is always translated as “degree” for the sake of uniformity. All the translator’s additions to the Kantian text are within square brackets. When the meaning of a word is translated in a form that departs from the original meaning due to context the Latin original is attached within round brackets in the grammatical form used by Kant. To facilitate understanding, long compound sentences of the Kantian text are sometimes broken up into several simple sentences. The structure of the text and title page format have been preserved. The translator would like to express sincere gratitude to Alexei N. Krouglov and Svyatopolk N. Yeschenko for their valuable advice, remarks and help and support in preparing this publication. (shrink)

Basically, the author places Heidegger's Sein and Seiende in a theological context; l'être is God, both present in the relations between les étants and absent as the Being of all beings. The task of ontology as a "topique de l'être" is to start with the "phenomenal situation" and dialectically make explicit the meaning of l'être in related "places", i.e., temporal consciousness, world, self, other, and love. The book suffers from scanty exposition and unacknowledged debts to Heidegger and to Merleau-Ponty--A. B.

In 2014, the editorial board of BMC Medical Ethics came together to devise sections for the journal that would give structure to the journal help ensure that authors’ research is matched to the most appropriate editors and help readers to find the research most relevant to them. The editorial board decided to take a practical approach to devising sections that dealt with the challenges of content management. After that, we started thinking more theoretically about how one could go about classifying (...) the field of medical ethics. This editorial elaborates and reflects on the practical approach that we took at the journal, then considers an alternative theoretically derived approach, and reflects on the possibilities, challenges and value of classifying the field more broadly. (shrink)

El presente trabajo recoge algunas consideraciones acerca de la significación y el valor teorético del . En la primera parte del trabajo se revisan las implicancias teoréticas del texto y su contexto. La segunda parte presenta el texto original del y una nueva traducción castellana lineal.